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READY-TO-USE FILM COATING
PHARMA ACRYLIC POLYMERS
R & D COATER
FILM COATING - NUTRACEUTICALS
CONTROLLED RELEASE PRODUCTS
AN EXPERT SYSTEM FOR DRUG DELIVERY SOLUTION.
With the evolution of pharmaceutical technology and understanding of human physiology and pathology, the need was to felt to control the time, site and rate of drug delivery. This gave rise to the so called Drug Delivery Systems. Modified Release Drug Delivery Systems form the major part of Drug Delivery Market.
With its background and technical know-how Ideal Cures has developed an expert system called ‘Instamodel’ Extended Release system based on predictive modelling for HPMC matrix tablets.
CONCEPT OF INSTAMODEL EXTENDED RELEASE SYSTEM:
The success of HPMC matrix tablet formulation depends upon the right selection of HPMC grade, diluents, their ratios and tablet geometry. Ideal Cures has done extensive work in this field using new techniques such as fractal geometry, actual experimentation and interpretation of the results so obtained. This has led to development of a sound technical database. Based on this database, Ideal Cures has developed a predictive computer model that could generate the exact blend of polymer and diluents required to achieve the target release profile. The user runs the trial at his/her end using the Instamodel blend and the API. In 80% of the cases, it was found that the developed blend and the formula met the target. In remaining cases, some fine tuning was required which was done simply by increasing or decreasing the ratio of the Instamodel blend to the drug.
THE INSTAMODEL SERVICE IS AVAILABLE IN TWO FORMS
1. INSTAMODEL BLEND
This is a proprietary, optimized blend of hypromellose polymers and tablet diluents. The start-up formula is generated by the INSTAMODEL predictive modeling system and supplied to the customer. The formulator is required to add the drug and processing aids and compress the blend.
2. INSTAMODEL ER
This is a proprietary, optimized blend of hypromellose polymers. This blend is developed using INSTAMODEL predictive modeling system. The formulator has to add suitable diluents and processing aids along with API to this blend and compress the matrix.
MECHANISM OF DRUG RELEASE FROM HYPROMELLOSE MATRICES:
SALIENT FEATURES OF INSTAMODEL SERVICE:
WORK FLOW OF INSTAMODEL - EXTENDED RELEASE SYSTEM:
APPLICATION EXAMPLES OF INSTAMODEL SERVICE:
More drugs under each category are available under INSTAMODEL Extended Release System.